S2E3 - Dog Genetics

Posted on Tuesday, Feb 16, 2021
In this episode, hosts Dr. Sabah Kadri and Arshi Arora discuss the genetics of our cute furry friends, the effects of domestication on natural selection and how years of in-breeding have led to the study of clear mappings between dog traits and gene variants. Our hosts gave each other a task to come up with some interesting traits and their genetic markers. A must listen.

Show Notes

References

Ostrander, E. A., & Wayne, R. K. The canine genome. Genome Research 15, 1706–1716 (2005) doi:10.1101/gr.3736605

Parker, H. G., et al. Genetic structure of the purebred domestic dog. Science 304, 1160–1164 (2004) doi:10.1126/science.1097406

Björnerfeldt, S., et al. Relaxation of selective constraint on dog mitochondrial DNA following domestication. Genome Research 16, 990–994 (2006) doi:10.1101/gr.5117706

Hosts

Arshi Arora

Arshi Arora

Arshi Arora is a Research Biostatistician at Memorial Sloan Kettering Cancer Center. She holds a double Masters of Science degree in Computational Biology and Biostatistics from Carnegie Mellon and Columbia University respectively. Her interests lie in creating elegant solutions to biological and clinical questions via simple yet compelling statistical models. She is a minimalist and follows an intense recycling waste regimen.

Sabah Kadri, PhD

Sabah Kadri, PhD

Dr. Sabah Kadri has a background in Computer Engineering with a PhD in Computational Biology from Carnegie Mellon University. Dr. Kadri leads a team of bioinformaticians and scientists to design, develop and implement cloud-based computational infrastructure and containerized bioinformatics software in clinical diagnostic services for germline and somatic next generation sequencing (NGS) testing. She has experience building clinical diagnostics pipelines and systems for adult and pediatric diseases and continues to work on informatics solutions and research questions for translational ‘omics’ and biomedical research to promote personalized medicine.

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